Table 1 Subject information

From: Diffuse optical tomography for the detection of perinatal stroke at the cot side: a pilot study

Subject ID

GA (weeks)

CGA at scan (weeks)

Respiratory

Neurology

Diagnosis/MRI findings

DOT channels incl. (%)

Stroke_1

38 + 4

38 + 6

HFNC

Apneas, Seizures

Perinatal stroke

Large hemorrhagic lesion in the left temporal lobe associated with overlying subdural hemorrhage; secondary to venous infarction

82.76

Stroke_2

37 + 2

37 + 3

SIMV+VG

Seizures

Left MCA infarct, HIE II

Abnormal signal intensities within the territory of the left MCA consistent with infarction. Involvement of the basal ganglia, thalami, and PLIC on the left with abnormal diffusion in the Left cerebral peduncle

79.31

Stroke_3

40

40 + 3

SVIA

Seizures

Right MCA infarct

Large infarct over the right hemisphere, involving the temporal, parietal, and occipital lobe

79.31

Stroke_4

41 + 3

41 + 6

SVIA

Seizures

Left MCA infarct

Abnormal signal intensity within white matter, cortex, and basal ganglia within the territory of the left MCA consistent with infarction

89.66

CTRL_1

37 + 5

38

SVIA

Normal

Healthy, no MRI

72.41

CTRL_2

40 + 1

40 + 2

SVIA

Normal

Healthy, no MRI

93.10

CTRL_3

31 + 5

34 + 3

SVIA

Normal

Healthy, no MRI

48.28

CTRL_4

37 + 2

37 + 3

SVIA

Normal

Healthy, no MRI

93.10

  1. Clinical details of the stroke-affected and control infants (CTRL)
  2. CGA corrected gestational age, DOT diffuse optical tomography, GA gestational age, HFNC high flow nasal cannula, HIE hypoxic ischemic encephalopathy, MCA middle cerebral artery, MRI magnetic resonance imaging, PLIC posterior limb of the internal capsule, SIMV+VG synchronized intermittent mandatory ventilation with volume guarantee, SVIA self-ventilating in air