Fig. 3

Volcano plots demonstrating that OIR was associated with alterations of specific genes in all analyzed time points (a—P12, b —P17, c—P28). I—gene expression changes in retina, II—gene expression changes in blood. The vertical axis value—negative log of the p-values. The horizontal axis—log2 change (FC—fold change) between the two experimental conditions (OIR vs. normoxia). The red dots represent genes, whose expression was significantly changed between the study vs. control groups (corrected p-value < 0.05)