Table 5 Top list of upregulated genes in retina and blood based on their expression fold change between OIR and control mice at different time points

 P12

Mri1

1.29

0.0338

Methylthioribose-1-phosphate isomerase

 P17

Esm1

49.02

1.3345E-11

Endothelial cell-specific molecule 1

Edn2

18.60

1.8853E-5

Endothelin-2

Bcl3

16.71

1.4607E-8

B-cell lymphoma 3 protein homolog

Apln

16.05

3.7819E-9

Apelin

C4b

11.10

1.3346E-11

Complement C4-B

Pcolce

10.65

6.6323E-11

Procollagen C-endopeptidase enhancer 1

Cebpd

10.47

1.9108E-8

CCAAT/enhancer-binding protein delta

Adm

9.68

7.5001E-11

Adrenomedullin

Tnnt2

8.46

3.2014E-8

Troponin T, cardiac muscle

Gfap

8.06

7.0122E-6

Glial fibrillary acidic protein

 P28

Bcl3

4.62

1.2942E-4

B-cell lymphoma 3 protein homolog

C4b

4.17

2.9285E-7

Complement C4-B

Lad1

3.92

0.0023

Ladinin-1

Apln

3.92

0.0012

Apelin

Pcolce

3.64

2.0317E-4

Procollagen C-endopeptidase enhancer 1

Fgf2os

3.22

0.0091

Uncharacterized protein

Tnnt2

2.86

2.8065E-5

Troponin T, cardiac muscle

Cebpd

2.77

6.8232E-4

CCAAT/enhancer-binding protein delta

Lyz1

2.64

0.0099

Lysozyme C-1

Glycam1

2.61

0.0187

Glycosylation-dependent cell adhesion molecule 1

 P17

Taf4

3.11

0.0403

Transcription initiation factor TFIID

Sec22a

2.96

0.0195

Vesicle-trafficking protein SEC22a

Trmt1l

2.91

0.0195

tRNA methyltransferase 1 -like protein

ND2

2.50

0.0070

NADH-ubiquinone oxidoreductase chain 2

Rrp1b

2.32

0.0067

Ribosomal RNA processing protein 1 homolog B

Trp53

2.25

6.9234E-4

Cellular tumor antigen p53

Fam20b

2.23

0.0481

Glycosaminoglycan xylosylkinase

Hmg20b

1.98

0.0067

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related

Gbf1

1.66

0.0304

Golgi-specific brefeldin A-resistance factor-1

Mkln1

1.60

0.0354

Muskelin