Fig. 6: Effect of high-frequency oscillatory ventilation (HFOV) on the rate of BPD at corrected 36 weeks of gestation in preterms with respiratory distress syndrome (RDS).
From: High-frequency ventilation in preterm infants and neonates
The studies are sub-grouped according to the applied ventilatory strategies as described by Thome et al.,89 including the more recent studies.83,84,85,86,87 Although an overall significantly lower rate of BPD was observed in the HFOV treated patients, this effect was only evident in studies comparing open lung HFOV strategies to CMV with a respiratory rate of ≤60/min. Comparing HFOV to unregulated CMV or high-rate CMV showed no difference in the pulmonary outcome at 36 weeks. “Events” columns show the number of children with moderate or severe BPD at 36 weeks, and “Total” columns show the number of subjects in the group. Horizontal bars indicate 95% confidence intervals.
