Fig. 1: Detection of CALPRO, LCN2, and HAPTO in the stools of NEC and non-NEC premature infants by ELISA. | Pediatric Research

Fig. 1: Detection of CALPRO, LCN2, and HAPTO in the stools of NEC and non-NEC premature infants by ELISA.

From: Lipocalin-2 and calprotectin as stool biomarkers for predicting necrotizing enterocolitis in premature neonates

Fig. 1

Stool samples analyzed were those collected over a 10-day period preceding NEC diagnosis (round symbols) and in matched non-NEC infants (square symbols). Simple linear regression for the levels of biomarkers in the stools were calculated for both NEC and non-NEC with R2 values varying between 0.02 and 0.0003 while the slopes were considered nonsignificant for all. For simplicity, only the regression line (black line, R2) for NEC samples are shown (left panels). The biomarker data were then subjected to ROC curve analyses (right panels) showing sensitivity and specificity values and cut-off evaluation (dotted lines *, left panels).

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