Table 3 Polysomnographic recording times and sleep characteristics.

From: Caffeine is a respiratory stimulant without effect on sleep in the short-term in late-preterm infants

 

1. Baseline

2. Caffeine

P value

Recording time (minutes)

223 (188–284)

183 (165–199)

0.002

Sleep efficiency (%)

74.0 (61.5–84.5)

83.0 (67.0–89.0)

0.16

TST (minutes)

166 (135–200)

152 (120–164)

0.054

 REM of TST (%)

53.0 (44.0–56.0)

48.0 (42.5–59.0)

0.63

 NREM of TST (%)

47.0 (44.0–55.5)

52.0 (41.0–57.0)

0.64

REM latency

1.0 (0.0–20.8)

0.0 (0.0–11.0)

0.55

Sleep stage transitions per hour

21.9 (18.45–27.6)

24.50 (18.9–28.7)

0.65

REM periods (minutes)

 Shortest

4.5 (4.0–6.0)

4.5 (4.0–6.3)

0.97

 Longest

25.5. (16.0–38.8)

23.0 (15.5–37.3)

0.95

 Average time

11.0 (8.3–15.2)

12.5 (9.0–16.2)

0.38

 Average interval

21.4 (13.3–29.7)

17.4 (14.1–27.1)

0.39

  1. Main sleep parameters remained unchanged during caffeine treatment. TST total sleep time, REM rapid eye-movement sleep, NREM non-rapid eye-movement sleep. Results presented as median (interquartile range).
  2. P = significance according to Wilcoxon signed-rank test of two related samples
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