Today we would like to note the passing of Dr. Kwang Sik Kim in the journal, Pediatric Research. Dr. Kim had along and notable career at the Johns Hopkins Children’s Center. He was Division Chief of Pediatric Infectious Diseases (2000–2021) and a professor in the Department of Molecular Microbiology and Immunology at the Johns Hopkins Bloomberg School of Public health. His major scientific contributions were in the area of central nervous system infections. His work was among the earliest to demonstrate the mechanisms used by pathogens to penetrate the blood–brain barrier and cause neurologic disease. His model has been used by investigators throughout the world to understand central nervous system infection and inflammation and was the basis for establishing novel concepts, such as the neurovascular impact of Alzheimer’s disease. In addition to his scientific rigor, he was committed to mentorship and training. Since arriving at Johns Hopkins in 2000, he secured and maintained a T32 training grant that has led to the development of many nationally recognized leaders in the field of pediatric infectious diseases. A lectureship fund, in collaboration with the Division of Pediatric Infectious Diseases, has been established to honor Dr. Kwang Sik Kim’s legacy. At Pediatric Research, we would like to express our gratitude for his many years of service. He served as both Associate Editor and Section Editor from 2011 until 2021. We will miss his many contributions to the journal, his sage advice at editorial board meetings, and his camaraderie. Thank you, Dr. Kim.