Table 1 Diagnostic criteria for ventilation-associated pneumonia in mechanically ventilated neonates according to the Centers for Disease Control and Prevention/National Nosocomial Infection Surveillance criteria for patients younger than 12 months of age.

From: Early molecular markers of ventilator-associated pneumonia in bronchoalveolar lavage in preterm infants

Type

Criteria

 

>48 h of mechanical ventilation

Radiologic

Persistent radiological infiltrates or consolidation in two sequential radiographs after initiation of mechanical ventilation

Clinical

Worsening of the respiratory conditions characterized by increased

 • need for supplemental oxygen

 • respirator settings to achieve targeted respiratory values

 • amount of respiratory secretions

 • incidence of desaturation events

Presence of tachypnea, apnea, and/or retractions

Microbiological

Isolation of any microorganism with more than 1000 CFU/mL in bronchoalveolar lavage fluid