Table 3 Distribution of the VDR Fok I genotypes, alleles, and serum 25-(OH) D in patients with COVID-19 and control group.

From: Vitamin D deficiency and vitamin D receptor FokI polymorphism as risk factors for COVID-19

Genotype

Patient group

Control group

OR (95% CI)

P

n (180), %

n (200), %

VDR Fok I

f/f

83 (46)

96 (48)

Referent

 

F/f

60 (33)

92 (46)

0.59 (0.38–0.91)

0.01

F/F

37 (21)

12 (6)

4.05 (1.95–8.55)

<0.001

Alleles

f

226 (62.8)

284 (71)

Referent

 

F

134 (37.2)

116 (29)

1.45 (1.06–1.99)

0.01

Serum 25(OH) D (ng/mL)

 

14.7 (6.4–53)

37.6 (10.3–72.8)

 

<0.01a

  1. Values in parentheses are percentages or data are presented as mean ± SD.
  2. VDR vitamin D receptor, OR odds ratio, CI 95% confidence interval.
  3. P value < 0.05 indicates a significant difference. Chi-square test.
  4. aStudent’s t test.
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