Fig. 4: Multi-analyte models based on the human milk (HM) metabolome and exposome predict the children’s future neurodevelopmental delay risk.
From: Metabolomic and exposomic biomarkers of risk of future neurodevelopmental delay in human milk
a The selected analytes in the predictive model for female infants. The notched box plots represent the minimum and maximum values (whiskers), the IQR (length of the box), and the 95% CI around the median (notches). n = 12 for the risk group and n = 30 for the TD group. b The ROC curve for female infants. c The nomogram for predicting the risk of NDD in females using the selected analytes from HM metabolome and exposome. Z-scores were used. d The selected predictive analytes for male children. n = 29 for the male TD group and 11 for the male risk group. e The ROC curve for male children. f The nomogram for predicting the risk of future NDD in male infants using the Z-scores of the selected analytes.
