Fig. 3: Microbiome changes as a function of treatment and response.

a Strain relative abundance before and after treatment (grouped by species). Detection of species at baseline vs. endpoint in the treatment vs placebo groups. b Difference in baseline microbial richness (at the order level) as a function of response rate. P value derived from a Wilcox test. Responders were defined as being in the treatment group and having at least one WBM increase.