Table 3 Model coefficients and 95% confidence intervals for the association between maternal occupational exposure to endocrine-disrupting chemicals (EDCs) and cognitive function at 5 years of age as measured by the McCarthy Scales of Children’s Abilities, INMA, 2003–2008 (N = 1058).

From: Correction: Maternal occupational exposure to chemicals and child cognitive function

EDC exposure

N

General Cognitive Index

Cognitive domains

Executive function

  

Verbal

Perceptual-performance

Quantitative

Memory

Motor

Individual EDC groups

        

 PAHs

41

−2.1 (−13.1, 8.8)

−2.2 (−11.9, 7.5)

−2.9 (−18.4, 12.6)

2.5 (−9.0, 14.0)

1.8 (−9.3, 12.8)

−1.9 (−13.8, 10.0)

−1.8 (−11.7, 8.0)

 Pesticides

13

5.3 (−7.7, 18.2)

9.3 (−8.5, 27.2)

−1.4 (−18.0, 15.3)

8.6 (−16.6, 33.8)

8.9 (−5.1, 22.8)

−3.4 (−11.5, 4.7)

3.4 (−6.5, 13.3)

 Phthalates

47

−2.2 (−9.2, 4.8)

−2.2 (−11.9, 7.6)

−0.4 (−8.8, 8.0)

−5.2 (−12.8, 2.3)

−2.6 (−10.8, 5.6)

−1.2 (−10.4, 8.0)

−2.4 (−9.4, 4.7)

 Organic solvents

182

−2.6 (−7.8, 2.7)

−1.1 (−6.4, 4.3)

−1.2 (−6.7, 4.3)

−5.8 (−11.0, −0.5)

−1.8 (−7.2, 3.5)

−1.5 (−7.4, 4.4)

−3.7 (−9.0, 1.6)

 Alkylphenolic compounds

152

−3.3 (−8.8, 2.2)

−2.0 (−7.8, 3.8)

−1.6 (−7.4, 4.3)

−5.6 (−11.4, 0.1)

−2.3 (−7.9, 3.4)

−1.3 (−9.1, 6.5)

−4.4 (−10.0, 1.2)

 Metals

46

2.4 (−10.6, 15.3)

2.1 (−12.6, 16.7)

0.5 (−8.7, 9.7)

2.3 (−6.9, 11.5)

4.1 (−6.1, 14.3)

2.3 (−7.4, 12.1)

2.1 (−11.1, 15.2)

 Miscellaneous

42

−2.7 (−10.3, 4.9)

−2.7 (−12.5, 7.1)

−0.2 (−8.9, 8.5)

−6.1 (−14.7, 2.5)

−3.4 (−11.9, 5.2)

−1.7 (−11.7, 8.4)

−2.7 (−10.7, 5.2)

Multiple EDC groups

        

 None

799

0 (reference)

0 (reference)

0 (reference)

0 (reference)

0 (reference)

0 (reference)

0 (reference)

 1 EDC group

92

0.2 (−7.1, 7.5)

−0.1 (−7.1, 6.9)

−0.3 (−8.0, 7.4)

1.4 (−6.2, 9.1)

1.8 (−5.9, 9.5)

−1.8 (−8.8, 5.3)

−0.4 (−7.8, 7.0)

 ≥2 EDC groups

167

−2.7 (−8.2, 2.7)

−1.4 (−7.5, 4.8)

−1.3 (−7.1, 4.3)

−5.1 (−10.6, 0.5)

−1.2 (−9.3, 6.9)

−0.9 (−9.5, 7.7)

−3.8 (−9.3, 1.7)

  1. EDC exposures were estimated using job-exposure matrix developed by Brouwers et al.6; miscellaneous chemicals include benzophenones, parabens, and siloxanes. Models are adjusted for maternal age, education, country of birth, parity, verbal intelligence quotient, pre-pregnancy body mass index and gestational weight gain, child sex, and age at assessment.
  2. PAH polycyclic aromatic hydrocarbon.
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