Table 3 Phase-I regression coefficients of the association of early-life adversity measures with infants’ cytokines and steroids.

From: Linking specific biological signatures to different childhood adversities: findings from the HERO project

Outcome

SES-D

GAD-2

FAD

CESD-8

N

R2

B

Std. B

FDR q

B

Std. B

FDR q

B

Std. B

FDR q

B

Std. B

FDR q

TNF-α pg/mL

0.13a

0.28

0.011

0.01

0.14

0.362

−0.01

0.00

0.657

0.00

−0.28

0.407

71

0.10

IL-1β pg/mL

0.10a

0.19

0.033

−0.02

−0.05

0.362

0.00

−0.02

0.863

0.00

−0.04

0.407

142

0.04

IL-6 pg/mL

0.03

0.06

0.524

0.02

0.06

0.362

−0.02

−0.10

0.303

0.01

0.06

0.407

138

0.02

IL-8 pg/mL

0.07

0.14

0.122

−0.01

−0.02

0.438

−0.01

−0.04

0.702

0.01

0.05

0.407

139

0.02

Cortisol pg/mg

−0.02

−0.02

0.871

−0.08

−0.15

0.362

0.08a

0.27

0.033

0.03

0.13

0.407

79

0.09

Cortisone pg/mg

0.00

0.00

0.995

0.02

0.08

0.362

0.05a

0.37

0.003

−0.02

−0.21

0.319

79

0.10

DHEA pg/mg

0.16a

0.35

0.011

0.03

0.14

0.362

0.00

0.00

0.982

−0.03

−0.28

0.294

76

0.09

  1. Note: bold values indicate FDR-adjusted significant associations (q < 0.05).
  2. SES-D socioeconomic disadvantage index, CESD-8 Center for Epidemiological Depression scale, GAD-2 Generalized Anxiety Disorder scale, FAD Family Assessment Device, Std. standardized.
  3. aSignificant at 5% bootstrap levels.