Table 4 Phase-II regression coefficients of the association of early-life adversity measures with infants’ cytokines and steroids.

From: Linking specific biological signatures to different childhood adversities: findings from the HERO project

Outcome

SES-D

GAD-2

FAD

CESD-8

N

R2

B

Std. B

FDR q

B

Std. B

FDR q

B

Std. B

FDR q

B

Std. B

FDR q

TNF-α

0.00

−0.01

0.935

0.08

0.19

0.216

0.01

0.04

0.352

−0.01

−0.10

0.320

126

0.03

IL-1β

0.06

0.11

0.247

0.05

0.09

0.334

0.01

0.05

0.352

−0.01

−0.05

0.420

126

0.02

Cortisol

0.00

0.00

0.980

0.05

0.05

0.379

−0.07

−0.25

0.352

0.01

0.03

0.421

49

0.05

Cortisone

−0.04

−0.08

0.562

−0.05

−0.09

0.334

−0.01

−0.09

0.352

0.07

0.39

0.035

50

0.13

DHEA

0.42a

0.65

<0.001

0.07

0.11

0.334

−0.01

−0.06

0.352

−0.03

−0.12

0.320

47

0.40

  1. Note: bold values indicate FDR-adjusted significant associations (q < 0.05).
  2. SES-D socioeconomic disadvantage index, CESD-8 Center for Epidemiological Depression scale, GAD-2 Generalized Anxiety Disorder scale, FAD Family Assessment Device, Std. standardized.
  3. aSignificant at 5% bootstrap levels.