Table 2 Cardiometabolic biomarkers of young adults born at very low birth weight and their controls, siblings born at term.

From: Cardiometabolic health in adults born with very low birth weight—a sibling study

Characteristic

VLBWa (n = 74)

Term-born sibling (n = 70)

 

mean (SD)

mean (SD)

Fasting glucose, mmol/l

5.4 (0.4)

5.3 (0.4)

30 min glucose, mmol/l

8.6 (1.7)

8.8 (1.4)

60 min glucose, mmol/l

8.6 (2.1)

8.4 (2.1)

120 min glucose, mmol/l

7.0 (1.8)

6.4 (1.6)*

Fasting insulin, mU/l

6.9 (3.7)

7.3 (4.4)

30 min insulin, mU/l

55.7 (32.5)

59.6 (35.3)

60 min insulin, mU/l

52.2 (31.3)

58.1 (41.4)

120 min insulin, mU/l

47.2 (43.0)

44.4 (39.4)

Fasting free fatty acids, mmol/l

0.64 (0.25)

0.57 (0.26)

30 min free fatty acids, mmol/l

0.30 (0.14)

0.32 (0.13)

60 min free fatty acids, mmol/l

0.12 (0.06)

0.11 (0.05)

120 min free fatty acids, mmol/l

0.05 (0.03)

0.05 (0.05)

Total cholesterol, mmol/l

4.7 (1.3)

4.6 (0.8)

HDL cholesterol, mmol/l

  Men

1.3 (0.3)

1.3 (0.3)

  Women

1.6 (0.4)

1.6 (0.4)

LDL cholesterol, mmol/l

2.8 (1.2)

2.7 (0.7)

Triglycerides, mmol/l

1.0 (0.6)

0.9 (0.4)

Homocysteine, μmol/l

2.0 (0.3)

2.0 (0.3)

Apolipoprotein A1, g/l

  Men

1.5 (0.2)

1.5 (0.2)

  Women

1.7 (0.3)

1.7 (0.3)

Apolipoprotein B g/l

  Men

0.9 (0.4)

0.9 (0.2)

  Women

0.8 (0.2)

0.8 (0.1)

Sex hormone binding globulin nmol/l

  Men

35.8 (16.6)

32.7 (12.1)

  Women

106.8 (82.9)

92.6 (69.5)

Testosterone, nmol/l

  Men

21.3 (6.7)

20.3 (5.8)

  Women

1.2 (0.5)

1.1 (0.6)

Uric acid, μmol/l

311.8 (79.0)

300.2 (65.7)

Ferritin, μg/l

71.3 (55.4)

82.2 (73.2)

High-sensitivity C-reactive proteinb, mg/l

1.5 (1.7)

1.5 (2.0)

Complement component C3, g/l

1.1 (0.2)

1.1 (0.2)

Complement component C4, g/l

0.2 (0.1)

0.2 (0.1)

Alanine aminotransferase, U/l

20.3 (14.0)

20.3 (13.1)

Aspartate transaminase, U/l

25.5 (8.9)

25.4 (6.8)

Alkaline phosphatase, U/l

66.0 (18.4)

68.2 (20.4)

  1. All results are presented as arithmetic means.
  2. *Denotes significant difference of p < 0.05.
  3. aVery low birth weight <1500 g.
  4. b4 participants had a high-sensitivity C-reactive protein >10 mg/l, these were excluded from analyses.