Table 4 Published target genes of miR-27a-3p that are also identified from our mRNA-seq screening (p < 0.05).
List | Gene ID | Gene names | References | Results from our screening (miR-27a-3p overexpression/control) | MiR-27a-3p-binding site (based on human gene sequence and prediction from the website at: https://www.targetscan.org/vert_80/) | |
|---|---|---|---|---|---|---|
p value | Ratio | |||||
1 | ENSG00000106683 | LIMK1 | 34 | 0.00007 | 0.414 | Position 1057–1064 of LIMK1 3’ UTR |
2 | ENSG00000253293 | HOXA10 | 35 | 0.0003 | 0.529 | Position 1032–1039 of HOXA10 3’ UTR |
3 | ENSG00000065559 | MAP2K4 | 36 | 0.001 | 0.749 | Position 2178–2185 of MAP2K4 3’ UTR |
4 | ENSG00000248866 | USP46 | 37 | 0.001 | 0.574 | Position 1367–1374 of USP46 3’ UTR |
5 | ENSG00000266094 | RASSF5 | 38 | 0.007 | 0.786 | Position 2045–2051 of RASSF5 3’ UTR |
6 | ENSG00000109670 | FBXW7 | 39 | 0.008 | 0.728 | Position 503–510 of FBXW7 3’ UTR |
7 | ENSG00000177885 | GRB2 | 40 | 0.011 | 0.823 | Position 2260–2267 of GRB2 3’ UTR |
8 | ENSG00000104332 | SFRP1 | 41 | 0.015 | 0.378 | Position 3030–3037 of SFRP1 3’ UTR |
9 | ENSG00000106799 | TGFβR1 | 42 | 0.037 | 0.786 | Position 1617–1623 of TGFBR1 3’ UTR |
10 | ENSG00000140092 | FBLN5 | 43 | 0.049 | 0.744 | Position 342–349 of FBLN5 3’ UTR |
