Fig. 5: Comparison of perfusion parameters in the central/thalamic (top) and peripheral parenchymal (bottom) regions by days on the EXTEND circuit where early, intermediate, and late examinations are ≤ 4, 5–8, and ≥ 9 days on circuit, respectively. | Pediatric Research

Fig. 5: Comparison of perfusion parameters in the central/thalamic (top) and peripheral parenchymal (bottom) regions by days on the EXTEND circuit where early, intermediate, and late examinations are ≤ 4, 5–8, and ≥ 9 days on circuit, respectively.

From: Unique model of chronic hypoxia in fetal lambs demonstrates abnormal contrast-enhanced ultrasound brain perfusion

Fig. 5

Centrally, greater differences in a Microvascular flow velocity (MFV) and b transit time are observed in early (8 data points) and late examinations (6 data points) but not in the intermediate group (14 data points). Differences in c microvascular blood flow (MBF) were only observed in the late group. In the peripheral parenchyma, significant differences in all perfusion parameters including d MFV, e transit time, and f MBF are observed with both intermediate and late experiments but not the early group. Significant results are denoted by an asterisk (*); MFV microvascular flow velocity, au arbitrary unit, s seconds, int intermediate, MBF microvascular blood flow.

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