Table 1 Comparison of contrast-enhanced ultrasound perfusion parameters between groups in the whole brain, central/thalamic region, and peripheral parenchyma (median ± interquartile range).

From: Unique model of chronic hypoxia in fetal lambs demonstrates abnormal contrast-enhanced ultrasound brain perfusion

 

Hypoxic

Normoxic

p value

MFV (au/s)

Whole brain

0.78 ± 0.36

1.1 ± 0.42

0.026*

Central/thalamic

1.32 ± 1.01

1.47 ± 0.88

0.11

Peripheral parenchyma

0.59 ± 0.51

0.84 ± 0.69

<0.001*

Transit time (s)

Whole brain

0.99 ± 0.46

0.63 ± 0.22

0.016*

Central/thalamic

3.65 ± 1.47

3.17 ± 1.33

0.08

Peripheral parenchyma

3.84 ± 1.99

1.87 ± 0.92

<0.001*

MBF (au2/s)

Whole brain

109 ± 84

181 ± 57

<0.001*

Central/thalamic

211 ± 136

242 ± 106

0.012*

Peripheral parenchyma

68 ± 27

102 ± 45

<0.001*

  1. MFV microvascular flow velocity, au arbitrary units, s second, MBF microvascular blood flow.
  2. * Denotes statistically significant results.
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