Table 2 Correlations between cardiac physiologic and contrast-enhanced ultrasound perfusion parameters in the whole brain, central/thalami, and peripheral parenchyma by group.

		CCO (cc/kg/min)				LVCO (cc/kg/min)				RVCO (cc/kg/min)				LVCO:RVCO
		Hypoxic		Normoxic		Hypoxic		Normoxic		Hypoxic		Normoxic		Hypoxic		Normoxic
		r	p	r	p	r	p	r	p	r	p	r	p	r	p	r	p
Whole brain	MFV (au/s)	−0.16	0.55	0.01	1	−0.13	0.63	0.01	0.97	0.03	0.89	0.05	0.87	−0.29	0.23	0.14	0.67
	Transit time (s)	0.15	0.56	−0.02	0.56	0.15	0.55	−0.04	0.91	0.04	0.81	−0.06	0.85	0.28	0.27	−0.16	0.61
	MBF (au²/s)	−0.16	0.54	0.13	0.68	−0.09	0.72	0.13	0.68	−0.06	0.81	0.11	0.74	−0.24	0.36	0.18	0.59
Central/thalamic	MFV (au/s)	−0.27	0.37	0.54	0.08	−0.06	0.83	−0.58	0.05	−0.14	0.63	0.49	0.11	−0.11	0.71	0.27	0.41
	Transit time (s)	0.17	0.56	−0.51	0.1	0.02	1	−0.56	0.06	0.03	0.94	−0.48	0.12	0.14	0.62	−0.29	0.38
	MBF (au²/s)	−0.12	0.68	0.48	0.12	0.07	0.81	0.51	0.1	−0.13	0.68	−0.39	0.21	0.041	0.89	0.32	0.29
Peripheral parenchyma	MFV (au/s)	−0.33	0.19	0.42	0.16	−0.05	0.86	0.42	0.18	−0.51	0.04*	0.37	0.23	−0.04	0.91	0.21	0.51
	Transit time (s)	0.25	0.32	−0.49	0.11	−0.01	0.99	−0.47	0.13	0.37	0.14	−0.44	0.16	0.19	0.52	−0.16	0.62
	MBF (au²/s)	−0.28	0.27	0.46	0.12	0.037	0.89	0.39	0.21	−0.48	0.06	0.37	0.22	−0.11	0.75	0.13	0.58

CCO combined cardiac output, LVCO left ventricular cardiac output, RVCO right ventricular cardiac output, cc cubic centimeter, kg kilogram, min minute, r Spearman’s rho, p p value adjusted, MFV microvascular flow velocity, au arbitrary units, MBF microvascular blood flow, s second
* Denotes statistically significant results.

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