Table 3 Studies describing use of amplitude-integrated EEG.
From: Neuromonitoring practices for neonates with congenital heart disease: a scoping review
Scope of Study | Number of neonates Mean [range] | Type of congenital heart disease (n) | Type of study (n) | Findings Summary | Citations | ||||
|---|---|---|---|---|---|---|---|---|---|
SVP | TGA | Heterogeneous CHDa | Case series | Cohort study | Other | ||||
Characterization of aEEG background in neonates with CHD (n = 3) | 53 [26,72] | 0 | 0 | 3 | 0 | 3 | 0 | -aEEG background in the postoperative period abnormal in almost half of neonates with CHD. -Seizures frequent and mostly subclinical. -Sleep-wake cycling impacted postoperatively and can be affected by sedatives. | |
aEEG as a predictor of neurodevelopmental outcome (n = 4) | 70 [32–150] | 0 | 0 | 4 | 0 | 4 | 0 | -There was a large heterogeneity of tests used to evaluate neurodevelopment and timing of evaluation. -Delayed return of sleep-wake cycling associated with worse neurodevelopmental outcomes. -Conflicting data on whether aEEG seizures were more likely to be associated with impaired development. | |
aEEG as a predictor injury on neuroimaging and outcome (n = 3) | 37 [10–76] | 0 | 0 | 4 | 0 | 3 | 0 | -Most studies were underpowered to demonstrate an association between aEEG abnormalities and neuroimaging abnormalities. | |
