Table 1 Number of positive cells by immunohistochemistry in one field of vision (at 40x) in germinal centers of palatine tonsils from PFAPA (n = 7) and control children with obstructive sleep apnea (n = 7).
PFAPA median (min-max) | Controls median (min-max) | P-value | |
|---|---|---|---|
Average mantle size (μm) | 180 (100–250) | 170 (150–200) | 0.847 |
Average interfollicular distance (μm) | 170 (150–250) | 220 (150–250) | 0.516 |
Average crypt width (μm) | 900 (500–1100) | 1100 (1000–1200) | 0.100 |
Average squamous epithelium width (μm) | 11000 (7000–16,000) | 8000 (6000–14,000) | 0.198 |
CD3 | 230 (140–280) | 250 (150–260) | 0.403 |
CD4 | 210 (126–250) | 200 (136–250) | 0.949 |
CD8 | 13 (8–22) | 18 (12–24) | 0.305 |
CD15 | 1 (0–2) | 0 (0–2) | 0.177 |
CD20 | 800 (500–900) | 820 (600–870) | 0.303 |
CD45 | 970 (640–1160) | 1020 (810–1080) | 0.405 |
CD56 | 0 (0–5) | 0 (0–0) | 0.142 |
CD61 | 0 (0–0) | 0 (0–0) | 1.000 |
