Table 2 Biochemical validation and categorization into TSE groups

From: Assessment, detection, and validation of clinical associations of thirdhand smoke exposure (ADVOCATE) study protocol

Screening and biochemical validation

NEG goal: N = 560

TEG goal: N = 240

MEG goal: N = 200

T0 screen indicates parent is a nonsmoker?

Yes

Yes

No

Salivary cotinine level

≤ 0.1 ng/ml

>0.1 ng/ml but <1 ng/ml

≥1 ng/ml

Hand wipe nicotine level

< 5 ng/wipe

≥ 5 ng/wipe

>5 ng/wipe

  1. TSE Tobacco smoke exposure, NEG no exposure group, TEG thirdhand smoke exposure-only group, MEG mixed secondhand smoke exposure + thirdhand smoke exposure group, T0 baseline.