Table 1 Comparison of baseline maternal and neonatal characteristics in the growth cohort in both epochs.

From: Improved linear growth after routine zinc supplementation in preterm very low birth weight infants

Characteristics

Epoch-1

Epoch-2

P-value

Maternal

N = 423

N = 302

 

Prenatal/first trimester maternal BMI (kg/m2)

32.50 ± 7.18 (366)

31.00 ± 8.23 (199)

0.03

Multiple gestation

54 (12.8%)

44 (14.6%)

0.48

Material community deprivation index > 0.3

316/422 (74.9%)

235/299 (78.6%)

0.25

Medicaid

375 (88.7%)

272 (90.1%)

0.55

Prenatal care

399 (94.3%)

279 (92.4%)

0.30

Pregnancy-induced hypertension

190 (44.9%)

128 (42.4%)

0.50

Diabetes mellitus

63 (14.9%)

56 (18.5%)

0.19

Antenatal steroids

380 (89.8%)

265 (87.7%)

0.38

Magnesium sulfate

240 (56.7%)

166 (55.0%)

0.45

Race/ethnicity

  

*0.27

Hispanic

282 (66.7%)

189 (71.6%)

 

Non-Hispanic Black

117 (27.7%)

62 (23.5%)

 

Non-Hispanic White

20 (4.7%)

8 (3.0%)

 

Other

4 (0.9%)

5 (1.9%)

 

Cesarean delivery

268 (63.4%)

206 (68.2%)

0.18

Neonatal

N = 480

N = 346

 

Female

224 (46.7%)

187 (54.0%)

0.04

Gestational age (weeks)

30.7 (28.3, 32.1)

30.8 (28.3, 32.1)

0.95

Gestational age <30 weeks

196 (40.8%)

139 (40.2%)

0.85

Birthweight (grams)

1403 (1090, 1690)

1430 (1030, 1720)

0.85

Weight Z-score

0.12 ± 1.18

0.08 ± 1.18

0.65

Arterial cord blood pH

7.25 ± 0.09 (314)

7.24 ± 0.09 (217)

0.62

Arterial cord blood base deficit (mmol/L)

−6.7 ± 4.1 (313)

−6.8 ± 3.9 (217)

0.71

Delayed cord clamping

-

20 (5.8%)

-

Apgar score at 5 min

8 (7,9)

8 (7,9)

0.46

Maximum FiO2 in delivery room

0.40 (0.30, 1.00)

0.40 (0.30, 1.00)

0.14

Endotracheal intubation in delivery room

56 (11.7%)

37 (10.7%)

0.66

Chest compressions in delivery room

4 (0.8%)

0 (0.0%)

0.14

Admission temperature (degrees centigrade)

36.3 ± 0.8

36.1 ± 0.7

< 0.001

Admission temperature

  

< 0.001

36.5–37.5 °C

158 (32.9%)a

78 (22.7%)b

 

< 36.5 °C

300 (62.5%)a

259 (75.5%)b

 

> 37.5 °C

22 (4.6%)a

6 (1.7%)b

 

Small for gestational age

58 (12.1%)

41 (11.8%)

0.92

Birth FOC (cm)

27.5 (25.5, 29.0)

27.5 (25.0, 29.5)

0.95

FOC Z-score

−0.07 ± 1.03

−0.06 ± 1.09

0.92

Accurate length in 1st week (cm)

38.7 (35.7, 40.7) (334)

38.8 (35.0, 41.2) (259)

0.51

Accurate length Z-score

−0.29 ± 1.94

−0.39 ± 0.88

0.36

BMI using first accurate length (kg/m2)

8.37 (7.56, 9.19) (334)

8.50 (7.54, 9.30)

0.44

BMI Z-score

−0.43 ± 1.42

−0.45 ± 2.24

0.86

  1. Values are mean ± SD (n if less than N in top row), median (IQR) or number (%).
  2. Student t-test, Mann-Whitney test, χ2 analysis or *Fisher’s exact test.
  3. a,bDifferent alphabetic superscripts across columns indicate significant pair-wise differences.
  4. BMI body mass index, FiO2 fractional inspiration concentration of oxygen, FOC fronto-occipital circumference.