Table 3 Change in Z-scores from birth to discharge in infants < 33 weeks or < 1500 g in the growth cohort during both epochs. a. Changes in weight, length and FOC. b. Change in length Z-scores: multivariate analysis.
From: Improved linear growth after routine zinc supplementation in preterm very low birth weight infants
a | |||||||
|---|---|---|---|---|---|---|---|
Variable | Unadjusteda | Adjusted for GA, postmenstrual age at discharge and Sexb | |||||
Epoch-1 | Epoch-2 | P-value | Sex | Epoch-1 | Epoch-2 | Epoch P-value | |
Delta WeightZ | −0.96 ± 0.74 N = 479 | −0.91 ± 0.76 N = 346 | 0.34 | Females Males | −0.94 ± 0.05 −1.00 ± 0.05 | −0.88 ± 0.05 −0.94 ± 0.05 | 0.27 |
Delta LengthZc | −0.94 ± 1.22 N = 351 | −0.70 ± 0.83 N = 308 | 0.003 | Females Males | −0.91 ± 0.06 −1.00 ± 0.06 | −0.65 ± 0.06 −0.74 ± 0.07 | < 0.001 |
Delta FOCZ | −0.29 ± 0.93 N = 470 | −0.39 ± 0.95 N = 340 | 0.13 | Females Males | −0.23 ± 0.06 −0.35 ± 0.06 | −0.32 ± 0.06 −0.45 ± 0.07 | 0.19 |
b | ||
|---|---|---|
Variable | Beta Coefficient (95% Confidence interval) | P-value |
Epoch-2 vs Epoch-1 | 0.27 (0.13, 0.42) | < 0.001 |
Gestational age (by week) | 0.23 (0.20, 0.26) | < 0.001 |
Antenatal steroids | −0.07 (−0.30, +0.17) | 0.58 |
Male | −0.11 (−0.26, +0.03) | 0.13 |
Race ethnicity | ||
Hispanic | (reference) | - |
Non-Hispanic Black | 0.05 (−0.11, +0.22) | 0.54 |
Non-Hispanic White | 0.24 (−0.15, 0.63) | 0.23 |
Other | 0.17 (−0.47, +0.82) | 0.60 |
Severe bronchopulmonary dysplasiad | 0.11 (−0.24, +0.45) | 0.55 |
Culture-positive late onset sepsis | 0.09 (−0.27, +0.44) | 0.64 |
Gastrointestinal perforation | −0.17 (−1.49, +1.14) | 0.80 |
Average energy intake (cal/kg/day)e | −0.02 (−0.03, −0.01) | 0.001 |
Average protein intake (cal/kg/day)e | 0.53 (0.24, 0.83) | < 0.001 |
