Table 4 Initial serum zinc level: Serum zinc level within the first 48 hours among infants born in Epoch-2 excluding infants on comfort care only and those with severe congenital anomalies. a. Quadratic normative regression vs gestational age. b. Multivariate analysis of the ratio of initial serum zinc level to GA-expected value from quadratic regression versus prenatal and early neonatal variables.

From: Improved linear growth after routine zinc supplementation in preterm very low birth weight infants

a

Variable

Beta coefficient (standard error)

95% Confidence interval

P-value

Gestational age (by week)

−0.2620 (0.1065)

−0.4708, −0.0532

0.014

Gestational age squared

+0.0036 (0.0018)

0.00002, 0.0072

0.049

Intercept

+5.580 (1.5309)

2.679, 8.580

< 0.001

b

Variable

Beta coefficient (standard error)

95% Confidence interval

P-value

Race/ethnicity

  

< 0.001

Hispanic

Ref

Ref

Ref

Non-Hispanic Black

0.030 (0.036)

−0.040, +0.100

0.40

Non-Hispanic White

−0.098 (0.109)

−0.311, +0.116

0.37

Other

−0.248 (0.038)

−0.321, −0.174

< 0.001

Maternal BMI (kg/m2)a

  

0.03

< 18.5

Ref

Ref

-

18.5– < 25

−0.445 (0.169)

−0.776, −0.113

0.009

25– < 30

−0.385 (0.168)

−0.714, −0.057

0.02

\(\ge 30\)

−0.357 (0.166)

−0.683, −0.032

0.03

Material community deprivation index > 0.30

−0.107 (0.042)

−0.189, −0.026

0.01

Prenatal care

+0.208 (0.039)

0.132, 0.285

< 0.001

Pregnancy-induced hypertension

0.100 (0.036)

0.030, 0.170

0.005

Antenatal steroids

−0.175 (0.045)

−0.263, −0.087

< 0.001

Intercept

+1.376 (0.176)

1.032, 1.721

< 0.001

  1. Generalized linear equation, n = 229.
  2. Stepwise generalized linear equation, n = 148.
  3. Not significant: maternal diabetes mellitus, medical insurance (Medicaid vs other or none), small for gestational age, sex.
  4. aPre-pregnancy or first trimester.
  5. BMI body mass index.