Fig. 1: Custom hardware and software for the real-time detection of immune cell biophysical signatures in NICU.
From: Whole blood biophysical immune profiling of newborn infants correlates with immune responses
a Illustrates the functions designed into the system including software and hardware controls. A disposable assay kit was developed for the point-of-care immune profiling test. b Shows the workings of the microfluidic device with blood cells (RBCs and WBCs) interacting with the unique pillar shape(s) array. WBC are displaced laterally away from the RBC flow stream and experiencing hydrodynamic forces while interacting with the pillars. Scale bar represents 40 µm. c Shows the real-time detection of WBC shown as a pink dot in the image (Supplementary Video S3 and S4). The histogram in the microfluidic chip represents the distribution of immune cell apparent diameter at a given flowrate. Scale bar represents 100 µm.
