Fig. 3: Representative H&E-stained microphotographs of the thalamus from female and male piglets showing necrotic-like (black arrows) and remaining living (arrowheads) cells.
From: Sex dimorphism in brain cell death after hypoxia-ischemia in newborn piglets
Original magnification: ×400. Inset magnification: ×630. Scale bar: 100 μm. Graphs: a Averaged number of necrotic cells per mm2 (pooled across regions and bregma 0/−2.0 levels) from females and males. The overall number of necrotic cells per mm2 was significantly (Unpaired t-test, ****p < 0.0001) higher in males versus females. AVG average. b Quantitative results of regional necrotic cell death between females and males. cTEX cingulate cortex, sTEX sensorimotor cortex, PvWM periventricular white matter, CDT caudate nucleus, THAL thalamus. Unpaired t-test for cTEX, sTEX, and THAL; Mann-Whitney for PvWM and CDT. **p < 0.01 or ***p < 0.001 or ****p < 0.0001 vs females.
