Fig. 4: Representative H&E-stained microphotographs of the sensorimotor cortex from female and male piglets showing apoptotic-like (black arrows) cells.
From: Sex dimorphism in brain cell death after hypoxia-ischemia in newborn piglets
Original magnification: ×400. Inset magnification: ×630. Scale bar: 100 μm. Graphs: a Averaged number of apoptotic cells per mm2 (pooled across regions and bregma 0/−2.0 levels) from females and males. The overall number of apoptotic cells per mm2 was significantly (Unpaired t-test, ****p < 0.0001) lower in males versus females. AVG average. b Quantitative results of regional apoptotic cell death between females and males. cTEX cingulate cortex, sTEX sensorimotor cortex, PvWM periventricular white matter, CDT caudate nucleus, THAL thalamus. Unpaired t-test for cTEX, CDT, and THAL; Mann-Whitney for sTEX and PvWM. ****p < 0.0001 vs females.
