Table 4 Comparison of baseline characteristics of children with unchanged or increased scores compared to children with scores that decreased between 18–24 months and 6–8 years.
From: Cognitive development at late infancy and school age in children cooled for neonatal encephalopathy
Characteristics | Children with unchanged/increased scores (n = 27) | Children with decreased scores (n = 22) | p-value |
|---|---|---|---|
Neonatal | |||
Sex | 0.040 | ||
Female, no. (%) | 7 (26) | 13 (59) | |
Male, no. (%) | 20 (74) | 9 (41) | |
Birth weight (g), mean (SD) | 3316 (490) | 3449 (556) | 0.382 |
Gestational age in weeks, mean (SD) | 39.9 (1.4) | 39.6 (1.8) | 0.538 |
Worst pH, mean (SD) | 7.0 (0.2) | 6.9 (0.1) | 0.326 |
Worst base excess, mean (SD) | −16.4 (6.2) | −19.4 (7.8) | 0.141 |
Apgar score at 10 min, median (IQR) | 6 (5–8) | 6 (2–8) | 0.740 |
Ventilation at 10 min, no. (%) | 18 (67) | 16 (73) | 0.884 |
aEEG category | |||
Moderately abnormal, no. (%) | 27 (100) | 19 (86) | 0.167 |
Severely abnormal, no. (%) | 0 (0) | 3 (14) | |
NE grade | |||
Moderate, no. (%) | 24 (89) | 15 (68) | 0.152 |
Severe, no. (%) | 3 (11) | 7 (32) | |
Neonatal MRI brain injury score, median (IQR) | 2 (0–3) | 2.5 (1–4) | 0.145 |
18–21 months | |||
Bayley-III CLC, mean (SD) | 101.7 (12.9) | 105.5 (8.8) | 0.222 |
6–8 years | |||
Weight, mean (SD) | 25.0 (4.2) | 25.7 (5.5) | 0.612 |
Head circumference, mean (SD) | 52.3 (1.3) | 52.5 (2.7) | 0.682 |
WISC-IV FSIQ, mean (SD) | 101.7 (9.9) | 87.5 (8.6) | <0.001 |
Index of multiple deprivation, median (IQR) | 7 (5–9) | 6.5 (4–8) | 0.367 |
