Fig. 4: Sexual dimorphism in E2 treated cytokine responses

Serum IL-1β (a), IL-18 (b), IL-1RA (c) and IL-33 (d) levels in E2-treated male (n = 16) and female (n = 16) term and preterm (n = 22 male and n = 18 female) neonates compared with baseline and LPS treated samples. Values displayed represent mean ± standard deviation of pg/ml. *=significant at p < 0.05; ns-non-significant.