Table 2 The results of the Linear Mixed Model analysis.

From: Total hydrocortisone dosage in extremely low birth weight infants and neurodevelopment up to school age

Linear Mixed Model Results

 

Non-Adjusted Model

Adjusted Model

Predictors

Estimates

CI

p

Estimates

CI

p

(Intercept)

86.99

83.85 – 90.13

 

88.65

84.65 – 92.74

 

Total HC dosage per 10 mg

−3.17

−4.48 – −1.86

<0.001

−2.82

−3.89 – −1.06

0.001

Time point

−0.57

−1.20 – 0.05

0.073

−0.57

−1.19 – 0.06

0.075

Total HC dosage per 10 mg: Time point

0.14

−0.14 – 0.41

0.334

0.10

−0.18 – 0.37

0.481

Severe complications: Yes (Sepsis, NEC (grades ≥ II), IVH (grades ≥ III), PVL: Any one of these yes)

   

−13.58

−19.84 – −7.31

<0.001

BPD: Yes

   

1.09

−3.44 – 5.62

0.637

LCC: Yes

   

−4.28

−9.89 – 1.34

0.135

Random Effects

σ2

85.45

85.37

τ00

178.26 Case number

156.77 Case number

N

165 Case number

165 Case number

Observations

396

396

  1. HC hydrocortisone, NEC necrotizing enterocolitis, IVH intraventricular hemorrhage, PVL periventricular leukomalacia, BPD bronchopulmonary dysplasia, LCC late-onset circulatory collapse.