Fig. 4: Blood immune genes are associated with gut parameters.

a Heatmap representation of Spearman’s correlation analyses between clinical parameters and qPCR-measured gene expressions related to the Toll-like receptor and JAK-STAT pathways from days 5 to 9. The heatmap color palette represents the lowest correlation coefficient values with cool colors, while warm colors represent the highest values. b–f Spearman’s correlation analyses between clinical parameters and CXCL9, CXCL10, and IL-6 expressions on day 5 in AB and CON groups, separately. ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001. CON control, AB antibiotics.