Table 1 Cohort characteristics
Characteristics | L-CDH (n = 1531) | R-CDH (n = 246) |
|---|---|---|
Neonatal Characteristics | ||
Male sex, n (%) | 883/1528 (57.8%) | 137/245 (55.9%) |
Estimated gestational age (EGA), weeks, median [IQR] | 38 [37–39] | 38 [36–39] |
Preterm (EGA < 34wk), n (%) | 61/1528 (4.0%) | 14/245 (5.7%) |
Birth weight, kg, mean ± SD | 3.0 ± 0.6 | 3.0 ± 0.6 |
Cesarean delivery, n (%) | 742/1511 (49.1%) | 122/243 (50.2%) |
Apgar at 1-minute, median [IQR] | 5 [3, 8] | 5 [3, 7] |
Apgar at 5-minute, median [IQR] | 7 [6, 9] | 7 [5, 8] |
Apgar at 5-minute ≤ 5, n (%) | 305/1434 (21.3%) | 65/228 (28.5%) |
CPR in the delivery room, n (%) | 98/1269 (7.7%) | 26/208 (12.5%) |
Inborn, n (%) | 940/1531 (61.4%) | 139/246 (56.5%) |
Prenatal diagnosis, n (%) | 1189/1530 (77.7%) | 161/245 (65.7%) |
Liver in chest, n (%) | 482/1384 (34.8%) | 197/215 (91.6%) |
Early iNO usea, n (%) | 725/1531 (47.4%) | 138/246 (56.1%) |
Repair Characteristics | ||
Timing of repair, days, median [IQR] | 4 [2, 6] | 5 [3, 8] |
Defect sizeb, n (%) | ||
A | 218/1531 (14.2%) | 13/246 (5.3%) |
B | 608/1531 (39.7%) | 76/246 (30.9%) |
C | 434/1531 (28.3%) | 96/246 (39.0%) |
D | 136/1531 (8.9%) | 32/246 (13.0%) |
Non-repair | 121/1531 (7.9%) | 27/246 (11.0%) |
Unknown | 14/1531 (0.9%) | 2/246 (0.8%) |
Patch repair, n (%) | 659/1406 (46.9%) | 143/216 (66.2%) |
Outcomes | ||
Death, n (%) | 254/1531 (16.6%) | 49/246 (19.9%) |
Age at death, days, median [IQR] | 11.5 [1, 31] | 4 [1, 19] |
ECLS use, n (%) | 264/1531 (17.2%) | 66/246 (26.8%) |
Days on ventilatorc, days, median [IQR] | 10 [6, 19] | 14 [8, 26.5] |
Days in hospitalc, days, median [IQR] | 35 [22, 63] | 53 [30, 86] |
Oxygen at dischargec, n (%) | 222/1276 (17.4%) | 63 /195 (32.3%) |
