Table 2 Logistic regression analysis for predicting adverse pathology in biopsy cohort

From: Validation of the Decipher Test for predicting adverse pathology in candidates for prostate cancer active surveillance

Model

Variable

Odds ratio (95% CI)

P-value

AUC (95% CI)

Univariable

CAPRA

1.42 (0.93–2.19)

0.109

0.57 (0.47–0.68)

Decipher

1.32 (1.07–1.63)

0.011*

0.65 (0.56–0.74)

Multivariable: CAPRA + Decipher

CAPRA

1.29 (0.84–2.00)

0.239

0.65 (0.58–0.70)a

Decipher

1.29 (1.03–1.61)

0.025*

 
  1. Odds ratios of Decipher were reported per 0.1 unit increase. 4 patients without CAPRA scores were excluded from models with CAPRA.
  2. *P-value < 0.05
  3. aAUC was adjusted for optimism
  4. CI confidence interval, AUC area under curve
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