Table 4 Logistic regression analysis for predicting adverse pathology using Decipher cut-point of 0.2 in biopsy cohort

From: Validation of the Decipher Test for predicting adverse pathology in candidates for prostate cancer active surveillance

Model

Variable

Odds ratio (95% CI)

P-value

Univariable

CAPRA

1.42 (0.93–2.19)

0.109

Categorical CAPRA Int. vs Low

1.51 (0.67–3.26)

0.311

Decipher

1.32 (1.07–1.63)

0.011*

Decipher > 0.2 vs ≤ 0.2

3.56 (1.39–11.43)

0.006*

Multivariable: CAPRA + Decipher

CAPRA

1.29 (0.84–2.00)

0.239

Decipher

1.29 (1.03–1.61)

0.025*

Multivariable: Categorical CAPRA + Categorical Decipher (cutpoint = 0.2)

Categorical CAPRA Int. vs Low

1.31 (0.58–2.86)

0.513

Decipher > 0.2 vs ≤ 0.2

3.17 (1.22–10.26)

0.016*

  1. Odds ratios of Decipher were reported per 0.1 unit increase. 4 patients without CAPRA scores were excluded in models with CAPRA.
  2. *P-value < 0.05
  3. CI confidence interval
Back to article page