Fig. 4 | Prostate Cancer and Prostatic Diseases

Fig. 4

From: Distinct transcriptional repertoire of the androgen receptor in ETS fusion-negative prostate cancer

Fig. 4

Specific AR target pathways show ETS status and BCR dependency. Gene ontology analysis and literature searches revealed that among ETS status-dependent AR target genes, metabolic pathway genes and non-canonical WNT pathway genes are up-regulated in ETS− tumors, whereas signaling and ion transport pathway genes are up-regulated in ETS+ tumors (a). Kaplan–Meier curves for metabolic (b) and non-canonical WNT (c) genes show significance to BCR in ETS+ tumors

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