Fig. 4
From: Distinct transcriptional repertoire of the androgen receptor in ETS fusion-negative prostate cancer

Specific AR target pathways show ETS status and BCR dependency. Gene ontology analysis and literature searches revealed that among ETS status-dependent AR target genes, metabolic pathway genes and non-canonical WNT pathway genes are up-regulated in ETS− tumors, whereas signaling and ion transport pathway genes are up-regulated in ETS+ tumors (a). Kaplan–Meier curves for metabolic (b) and non-canonical WNT (c) genes show significance to BCR in ETS+ tumors