Table 1 Multivariable Cox proportional hazard regression analysis for PCS and PAM50 classification with clinical parameters.
From: A comparative study of PCS and PAM50 prostate cancer classification schemes
Multivariable analysis with PCS | Multivariable analysis with PAM50 | ||||||
|---|---|---|---|---|---|---|---|
Variable | Hazard ratio | p value | C-index | Variable | Hazard ratio | p value | C-index |
PCSM | |||||||
PCS | 3.76 (2.17–6.52) | <0.001 | 0.75 | PAM50 | 1.51 (0.96–2.38) | 0.073 | 0.75 |
Gleason score | 2.16 (1.74–2.66) | <0.001 | Gleason score | 2.25 (1.83–2.78) | <0.001 | ||
BCR | |||||||
PCS | 2.03 (1.39–2.96) | <0.001 | 0.66 | PAM50 | 1.43 (1.14–1.79) | 0.002 | 0.67 |
Gleason score | 1.71 (1.55–1.88) | <0.001 | Gleason score | 1.69 (1.54–1.86) | <0.001 | ||
Met | |||||||
PCS | 3.38 (2.26–5.06) | <0.001 | 0.71 | PAM50 | 1.73 (1.30–2.29) | <0.001 | 0.72 |
Gleason score | 2.03 (1.79–2.31) | <0.001 | Gleason score | 2.04 (1.80–2.32) | <0.001 | ||
