Table 1 The studies’ characteristics of all included articles.
First author of study and [Ref.] | Country | Recruitment period | Study design | Level of evidence | Definition of FH | Total | FH | NOS | |
|---|---|---|---|---|---|---|---|---|---|
Yes | No | ||||||||
Hanus et al. [24] | US | 1987–1996 | Cohort, retrospective | 2B | One or more first-degree relatives | 1164 | 148 | 1016 | 6 |
Ray et al. [25] | US | 1983–2001 | Cohort, retrospective | 2B | One or more first-degree relatives | 536 | 97 | 439 | 7 |
Lee et al. [26] | US | 1989–2000 | Cohort, retrospective | 2B | One or more first-degree relatives | 556 | 103 | 453 | 7 |
Spangler et al. [27] | US | 1995–2002 | Cohort, retrospective | 2B | One or more first-degree relatives | 506 | 179 | 327 | 6 |
Roehl et al. [28] | US | 1983–2003 | Cohort, retrospective | 2B | One or more first-degree relatives | 1186 | Sibiling pairs (n = 141) Hereditary (n = 114) High density family member (n = 37) | 968 | 7 |
Kupelian et al. [29] | US | 1986–2002 | Cohort, retrospective | 2B | One or more first-degree relatives | 4112 | 659 | 3453 | 7 |
Peters et al. [30] | US | 1992–2005 | Cohort, retrospective | 2B | One or more first-degree relatives | 1737 | 187 | 1550 | 7 |
Bagshaw et al. [31] | US | 1989–2007 | Cohort, retrospective | 2B | One or more first-degree relatives | 1711 | 386 | 1325 | 7 |
Westerman et al. [13] | US | 1987–2010 | Cohort, retrospective | 2B | One or more first-degree relatives | 16,472 | 5323 | 11,149 | 7 |
Thalgott et al. [32] | Germany | 1994–2010 | Cohort, retrospective | 2B | HPC: subgroup of familial PCa with a likelihood of genetic predisposioton SPC: two or more brothers aged at least 60 y and negative anamnesces for PCa | 11,130 (FPC + SPC n = 2775) | HPC (n = 807) FPC (n = 2251) | Non-FPC (n = 8072) SPC (n = 524) | 7 |
Lee et al. [6] | Korea | 2006–2015 | Cohort, retrospective | 2B | One or more first-degree relatives | 606 | 39 | 567 | 6 |
