Table 3 Performance of the EPI test with a cut point of 15.6 in the pooled cohort.

From: Predicting high-grade prostate cancer at initial biopsy: clinical performance of the ExoDx (EPI) Prostate Intelliscore test in three independent prospective studies

 

EPI ≥ cut point

EPI < cut point

Total

Performance

(95%CI)

Biopsy positive/≥GG2

338

28

366

Sensitivity, 92.3%

(89.1–94.9)

Biopsy negative/GG1

591

255

846

Specificity, 30.1%

(27.1–33.4)

Total

929

283

1212

PPV, 36.4%

(33.3–39.6)

    

NPV, 90.1%

(86.0–93.3)

Prevalence

30.2%

Predicted negative

23.3%