Fig. 2 | Signal Transduction and Targeted Therapy

Fig. 2

From: miRNAs reshape immunity and inflammatory responses in bacterial infection

Fig. 2

Representative miRNAs in the regulation of autophagy. Autophagy is an important immune response used to eliminate bacterial pathogens. In turn, bacterial pathogens have also developed the ability to subvert host autophagy by interfering with autophagy signaling. Deregulation of miRNAs can occur as the result of interplay between bacterial factors and autophagy components. miRNAs that target autophagy-related proteins function as a specialized immunologic effector and effectively regulate host innate immune responses for the elimination of pathogenic bacteria

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