Fig. 2 | Signal Transduction and Targeted Therapy

Fig. 2

From: Increased mtDNA copy number promotes cancer progression by enhancing mitochondrial oxidative phosphorylation in microsatellite-stable colorectal cancer

Fig. 2

Increased mtDNA copy number promoted cell proliferation of MSS CRC cells. a, b Cell proliferation was evaluated with an EdU incorporation assay in SW480 and Caco-2 cells with the indicated treatments. Scale bar: 50 μm. c Representative immunohistochemical (IHC) staining images of Ki-67 in xenograft tumors developed from SW480 cells that were stably transfected with different expression vectors as indicated. Scale bar: 100 μm. The data shown are the mean ± SEM from three separate experiments. *P < 0.05; **P < 0.01

Back to article page