Fig. 4 | Signal Transduction and Targeted Therapy

Fig. 4

From: The role of autophagy in colitis-associated colorectal cancer

Fig. 4

Role of macrophage autophagy on colitis and colorectal cancer. a Autophagy can inhibit inflammation through inhibiting bacteria invasion; promoting antigen processing; inhibiting M1 polarization and activating M2 polarization; and suppressing the NLRP3 inflammasome and other PRRs. b Autophagy can inhibit CRC through inhibiting oncogenesis, angiogenesis and tumor growth; and increasing the radiosensitivity of CRC cells. MTMR3 myotubularin-related protein 3, CB2R cannabinoid receptor 2

Back to article page