Table 1 Characteristics of cRGD-PS-Dox and PS-Dox

From: Targeted chemotherapy for subcutaneous and orthotopic non-small cell lung tumors with cyclic RGD-functionalized and disulfide-crosslinked polymersomal doxorubicin

Polymersomes

DLCa (wt.%)

   
 

Theory

Determined

DLEa (%)

Sizeb (nm)

PDIb

PS-Dox

9.1

6.7

72.1

85

0.08

 

16.7

12.0

68.4

88

0.11

 

23.1

15.5

61.3

94

0.13

cRGD-PS-Dox

9.1

6.8

73.5

82

0.06

 

16.7

11.8

67.2

86

0.12

 

23.1

15.2

59.6

96

0.13

  1. aMeasured by fluorometry
  2. bMeasured by DLS at 25 °C in PB (polymersome concentration: 1.0 mg/mL)
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