Fig. 5
From: miR-23a promotes invasion of glioblastoma via HOXD10-regulated glial-mesenchymal transition
MiR-23a promotes tumor invasion of glioblastoma via reduced HOXD10. a Wound-healing assays were performed with miR-23a-overexpressing U373 and LN443 cells and their respective control cells. Representative photomicrographs at 0 and 24 h are shown. b The distances moved are displayed as the mean ± SD. N.S. indicates not statistically significant. c Matrigel invasion assays were performed with both U373 and LN443 cells with or without forced miR-23a or HOXD10 expression. Micrographs of invading cells stained with crystal violet are displayed. d In the Matrigel invasion assays, the invaded cells under the filter were counted in three randomly selected regions, and graphed as the mean ± SD. e (Left) Micrographs of U87 cells with or without forced HOXD10 expression are displayed. (Right) In the Matrigel invasion assays, invaded cells were counted, and the data are presented as the mean ± SD. * P < 0.01 vs. control cells
