Fig. 1

GLPT inhibits cell proliferation and induces cell death in lung cancer cells. a–d A549 and A427 cells were treated with GLPT (0–1 mg/ml) for 3 or 5 days and then subjected to cell counting (a, b) or one-solution assay (c, d). e–g The indicated cells were treated with GLPT (0–1 mg/ml) for 72 h and then analyzed with trypan blue exclusion assay (e) or with annexin V-PI staining followed by flow cytometry (f, g). Representative images of the flow cytometry results are shown in (f), and the quantitative data are presented in (g). All data represent the mean ± SD (n = 3). GLPT treatment versus control (0 mg/ml GLPT), *P < 0.05; **P < 0.01; ***P < 0.001