Fig. 5
From: ReishiMax inhibits mTORC1/2 by activating AMPK and inhibiting IGFR/PI3K/Rheb in tumor cells
GLPT-mediated inhibition of mTORC1/2 is associated with activation of AMPK and inhibition of IGFR/PI3K/Rheb. a–d A549 cells (a–c) or A549 cells infected with Ad-AMPK-dn or Ad-GFP (control) (d) were treated with GLPT for 24 h at the indicated concentrations, and western blotting was then performed with the indicated antibodies. β-Tubulin served as a loading control
