Table 3 Molecular classification of HCC

From: Targeted therapy for hepatocellular carcinoma

Researcher

Year

Classification

Type

Case no.

Boyault et al.

2007

G1–G6

Transcriptome

57

Hoshida et al.

2009

S1–S3

Transcriptome

603

Schulze et al.

2015

Msig 1–6

Exome sequencing

243

/

2017

iC1–iC3

Multiomocis

363 + 196

Sia et al.

2017

25% HCCs with adaptive or exhausted immune responses

Immune cell profiling

956

Kurebayashi et al.

2018

Immune-high, -mid, and –low

Immuno-microenvironment

158

Shinata et al.

2019

MS-1, −2-, −3

Transcriptome and gonome

183

Jiang et al.

2019

S-I, S-II and S-III

Proteomics

110