Table 2 Side effects in patients receiving UC-MSCs infusions

From: Human umbilical cord-derived mesenchymal stem cell therapy in patients with COVID-19: a phase 1 clinical trial

Patient number

Clinical disease severity

Infusion round

EKG monitoring

POS monitoring (%)

Infusion associated events

Patient T1

Moderate

First infusion

Normal

98

Facial flushing occurred within 4 h after UC-MSCs transfusion and spontaneously relieved within 24 h

Patient T4

Moderate

Third infusion

Normal

100

Transient fever no more than 38 °C within 2 h after UC-MSCs transfusion and spontaneously relieved within 24 h

Patient T6

Severe

First infusion

Normal

91–99

Severe hypoxemia occurred within 12 h after UC-MSCs transfusion, believed to be associated with the progression of COVID-19, and recovered after HFNC (Humidified high-flow nasal cannula oxygen therapy)

  1. EKG electrocardiography, POS pulse oxygen saturation