Fig. 4: Chromatin profiles of FOXC1 occupancies in LSCs. | Signal Transduction and Targeted Therapy

Fig. 4: Chromatin profiles of FOXC1 occupancies in LSCs.

From: Loss of FOXC1 contributes to the corneal epithelial fate switch and pathogenesis

Fig. 4

a Barplot showing the distribution patterns of FOXC1 and ATAC peaks in LSCs. b Metaplot showing the average FOXC1, H3K4me2, and ATAC enrichment signals around the center of FOXC1 peaks. c Heatmaps showing the binding signals of FOXC1, ATAC, and H3K4me2 at the center of FOXC1 peaks. d Genome browser tracks for FOXC1, H3K4me2, and ATAC enrichment signals across the FOXC1 locus. e Metaplot showing the average FOXC1, H3K4me2, and ATAC enrichment signals around the center of TSSs. f Motifs enriched in ATAC and FOXC1 peaks. g Frequencies of PAX6, TP63, and KLF4 motifs around the centers of FOXC1 and ATAC peaks

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