Fig. 6 | Signal Transduction and Targeted Therapy

Fig. 6

From: A novel silicone derivative of natural osalmid (DCZ0858) induces apoptosis and cell cycle arrest in diffuse large B-cell lymphoma via the JAK2/STAT3 pathway

Fig. 6

DCZ0858 inhibited tumor growth in vivo. a Tumor specimens photographed with a high-definition digital camera. b Tumor volume was measured every 2 days. c The weight of the mice was recorded every 2 days. d H&E staining of the control and DCZ0858-treated transplanted tumor tissues in the nude mice (original magnification: ×400); e Apoptotic cells from the xenograft tumors in the nude mice as detected by TUNEL staining (magnification: ×400). f Ki67 staining of the control and DCZ0858-treated xenograft tumor tissues (original magnification: ×400). g H&E staining of the control and DCZ0858-treated heart, liver, kidney, spleen, and lung tissues in the nude mice (original magnification: ×200); *P < 0.05 and **P < 0.01

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